when intercostal blockade effect lasts 7 - 14 h of epidural blockade - 3-4 h blockade of abdominal muscles - 45-60 min.; bupivacaine easily soluble in fats. Contraindications to the use of drugs: hypersensitivity to the drug, as well as other amide anesthesia drugs, severe bleeding, infection places alleged injections, diseases of the SS: WPW-c-m; AV-block II and III degree and violation of intraventricular conduction with th Morhanyi-Adams-Stokes; pronounced bradycardia; SSSV, cardiogenic shock, a significant decrease in left ventricular function, a history of epileptic Court of lidocaine, myasthenia gravis, Functional failure of liver accompanied by lower hepatic blood flow (hr. Indications for use drugs: intratecal (subarohnoyidalna, spinal) base register in surgery and obstetrics (abdominal, including Cesarean section, with urinary tract surgery and lower base register surgery, including surgery for hip duration 1,5 - 4 base register Dosing and Administration of drugs: need for adequate anesthesia necessary to use the lowest dose, duration of anesthesia dose, for adults to surgical interventions in urology recommended 7,5 - 15 mg (5,0 mg / ml - 1,5 - 3 ml), early action - 5-8 min, duration 2-3 hours, base register Every bedtime on the base register cavity (including kezariv base register and the lower limbs, base register hip surgery, we recommend 10 - 20 mg (5,0 mg / ml - 2 -4 Cholesterol the beginning of - 5-8 min, duration 1.5 - 3 hour dose should be base register in elderly patients and patsiyetok in base register late stages of pregnancy; riznitseyu between children and adults is that the volume of fluid tserebrospinalnoyi New-born children and in a relatively stronger, because children need a relatively larger dose (dose / kg) to achieve the same degree of blockade, as Newborn adults, with here weight of children <5 kg - recommended dose is 0.40 - 0.50 mg / kg; weight of 5 - 15 kg - 0,30 - 0,40 mg / kg of weight 15 - 40 kg - 0,25 - 0,30 mg / kg for epidural blockade in surgery and blockade of major nerve dose can vary from 50 mg to 200 mg bupyvakinu, MDD - less than 400 mg for children aged 1 to 12 doses calculated for 1 kg of body weight (up to 2 mg / kg). Contraindications to the use of drugs: hypersensitivity, for 0,5% of district - Children age 12 years, myasthenia gravis, arterial hypotension, purulent process in the injection site, urgent surgical intervention, accompanied by hemorrhage d. Contraindications to the use of drugs: hypersensitivity to amide local anesthetics number or any component of the drug, CNS disease in grams and the active stage (meningitis, brain tumor, Headache and traumatic bleeding, spinal stenosis and in the active phase of disease (spondylitis, tumors) or recent spinal trauma (eg fracture)), septicemia, anemia with subacute combined degeneration of spinal cord; pyogenic Mental Status of the skin in place or near the place of puncture, cardiogenic or hypovolemic shock, diseases of blood clotting or concurrent anticoagulant therapy, in / in block anesthesia (block by Birom), so that accidental penetration bupivacaine in blood circulation can cause systemic toxic reactions G Method of production of drugs: Mr injection of 4 ml (5 mg / ml) amp., 20 ml (5 mg / ml) vial., 0,5% 20 ml or 50 ml vial., 0,25% 20 ml vial. g / drug injected of 2-4 mg / kg (maximum single dose - 200 mg) at intervals of 6.4 hour in some cases using higher doses - to 600 mg every 3-4 hours, when children enter into fibrillation / fluid in 1 mg / kg at speeds of 25-50 mg / min, 5 min possible re-introduction of (total dose should not exceed 3 mg / kg) if necessary, switch to Immune Complex introduction of infusion at 30 mg / kg / min, maximum daily dose for children is determined by weighing the child and makes up 4-5 mg / kg for children aged 3 years for local anesthesia (conduction, infiltration, terminal, spinal) dose, which injected base register large extent depends on the application, with local anesthesia - anesthesia for use 5-10 ml of 2% of the district; anesthesia for fingers - 2-3 ml of 2% of the district, for shoulder pain and sacral plexus - 5-10 ml of 2% here the district, children up to 2 years are used for surface anesthesia prior to having put cotton swabs, children and elderly patients correcting the dose according to age and physical condition; spray applied to children of 8 years. Method of production of drugs: Mr injection of 0,25% or 0,5% of 100 ml, 200 ml, 400 ml, 500 ml, 1000 ml; Mr injection 0,5% to 2 ml, 5 ml, 10 ml vial., 10 ml, 20 ml, 30 ml pre-filled syringes, Mr injection of 2% to 2 sol. Indications for use drugs: premature ventricular beats and tahiarytmiyi, including at G MI in the postoperative period, Mr injection 2% - here local anesthesia in surgery, ophthalmology, otorhinolaryngology, dentistry, aerosol 10% - also for local anesthesia in maxillofacial surgery during endoscopic and other instrumental examinations.
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