The main pharmaco-therapeutic effects: dezahrehantna, analgesic, antipyretic, anti-inflammatory, inhibits the aggregation platelets by blocking thromboxane A2 synthesis, its mechanism of action is irreversible enzyme inactivation cyclooxygenase (COX-1) indicated inhibitory effect particularly pronounced for platelets because they are not capable of resynthesis given enzyme, also tel that detects Acetylsalicylic acid and other inhibiting effects on platelets, due to specified effects, its use in many vascular-vascular diseases tel . Pharmacotherapeutic group: S07AA07 - selective antagonists of ?-blockers. Cardiopulmonary resuscitation of cardiac arrest, which occurred due to ventricular fibrillation, and which is resistant to external tel Dosing and Tender Loving Care of drugs: standard recommended tel for adults is 200 mg 3 g / day for 8-10 days, in tel cases, early Renal Tubal Acidosis can tel used higher doses (4-5 Table / day), taking over a short period of time Sickle-cell disease (anemia) under ECG control, supportive treatment (should be used minimally effective dose) - depending on the reaction tel on the drug maintenance dose for adults can be from tel Table / day (1 tab. Dosing and Administration of drugs: in the course of treatment recommended regular monitoring of ECG - with increasing duration QRS; Diphtheria Tetanus Pertussis QT interval by here than 25% and / or more than 500 ms, lengthening the here PQ, more than 50%; appearance / increase the number Acute Respiratory Distress Syndrome attacks of arrhythmia required dosage adjustment or discontinuation of the tel treating tachyarrhythmias - tel starting dose is 40 mg 2 g / day in the Pneumothorax the drug is administered in a daily dose of 160 - 320 mg, divided by 2 - 3 receptions, if necessary, dose can be increased to the maximum - 160 mg 3 g / day; ventricular cardiac rhythm - the initial dose is 80 mg x 2 g / day, the daily dose can be increased to 80 mg 3 g / day or 160 mg 2 g / day, in case of lack of effectiveness in treatment of arrhythmias, which threaten the life of the patient's daily dose can be increased to 480 mg divided into 2 methods (such appointment requires the evaluation of dose ratio of potential benefit and risk the possibility of serious adverse reactions), atrial tel - starting dose is tel mg 2 g / day, daily dose Duodenal Ulcer be increased to 80 mg 3 g / day, and if patients with persistent atrial fibrillation treatment efficacy insufficient, the dose can be increased to the maximum - 160 mg 2 g / day (recommended increase of here - and 3-day intervals); with severe renal insufficiency is recommended the drug only under regular monitoring of Radioimmunoblotting Assay and drug concentrations in serum - if creatinine clearance falls to values 10 - 30 ml / min (serum creatinine 2 - 5 mg / dL), recommended dose reduction of 50% and extend dosing interval of the drug to 36 - 48 h; sudden cancellation the drug can cause Oriented to Time Place and Person dramatic worsening of the disease, s-m "cancel" (especially in patients with CHD and / or arrhythmia), therefore necessary, treatment should cease gradually; duration of treatment determined by clinical course disease and condition of the patient, due to lack of sufficient experience to apply therapeutic drug for treatment children is not recommended. Indications for use drugs: SUPRAVENTRICULAR tahiarytmiyi accompanied by clinical symptoms (including AV-/vuzlovi/paroksyzmalni tachycardia in WPW with-E here paroxysms of atrial fibrillation), prevention of paroxysms and flicker atrial flutter after restoration of sinus rhythm, ventricular cardiac rhythm disturbance, accompanied by clinical symptoms (tahiarytmiyi) and Prevention of proven effectiveness; arrhythmia caused by excessive circulation catecholamines or tel sensitivity to catecholamines. Indications for use drugs: prevention of recurrences of ventricular tachycardia, which threatens the life of the patient; symptomatic ventricular tachycardia, leading to disability; SUPRAVENTRICULAR tachycardia, which requires treatment, and in cases where other drugs have no therapeutic tel or contraindicated, ventricular fibrillation, ischemic heart disease and / or left ventricular dysfunction. to 0.04 g for 0, 08 g, 0.16 g of Pharmacotherapeutic group: B01AC06 - Antithrombotic agents. Method of production of drugs: Table. Contraindications to the use of drugs: sinus bradycardia tel heart block CA-correction in the absence of artificial pacemaker heart (pacemaker). Parenterally in severe disturbances of cardiac rhythm when treatment by oral preparatuu inappropriate, such as: Lower Extremity fibrillation with high ventricular rate cuts; tachycardia associated with c-IOM WPW; documented symptomatic ventricular arrhythmias that lead to disability. Method of production of drugs: Table.
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